Polyclonal Antibody For Rat ACE

Cat.:P0004Rb-r 

Packing:40ug/0.2ml

Gene name:Ace(Dcp1); 

Protein name:Angiotensin-converting enzyme(ACE); 

Alternative: Dipeptidyl carboxypeptidase I;Kininase II; 

CD: CD143; 

Organism:Rat (Rattus norvegicus).  

General Annotation

Sub Unit:N/A 

Function:Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI-anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety. This GPIase activity seems to be crucial for the egg-binding ability of the sperm. 

Subcellular Location: Cell membrane Single-pass type I membrane protein 

Protein Attributes: 

Sequence length:1313 

Sequence:

50:MGAASGQRGR | WPLSPPLLML | SLLLLLLLPP | SPAPALDPGL | QPGNFSADEA |  

100:GAQLFADSYN | SSAEVVMFQS | TAASWAHDTN | ITEENARLQE | EAALINQEFA |  

150:EVWGKKAKEL | YESIWQNFTD | QKLRRIIGSV | QTLGPANLPL | TQRLQYNSLL |  

200:SNMSRIYSTG | KVCFPNKTAT | CWSLDPELTN | ILASSRNYAK | VLFAWEGWHD |  

250:AVGIPLRPLY | QDFTALSNEA | YRQDGFSDTG | AYWRSWYESP | SFEESLEHLY |  

300:HQVEPLYLNL | HAFVRRALHR | RYGDKYINLR | GPIPAHLLGD | MWAQSWENIY |  

350:DMVVPFPDKP | NLDVTSTMVQ | KGWNATHMFR | VAEEFFTSLG | LSPMPPEFWA |  

400:ESMLEKPADG | REVVCHASAW | DFYNRKDFRI | KQCTRVTMDQ | LSTVHHEMGH | 

450:VQYYLQYKDL | HVSLRRGANP | GFHEAIGDVL | ALSVSTPAHL | HKIGLLDRVA |  

500:NDIESDINYL | LKMALEKIAF | LPFGYLVDQW | RWGVFSGRTP | PSRYNYDWWY |  

550:LRTKYQGICP | PVARNETHFD | AGAKFHIPSV | TPYIRYFVSF | VLQFQFHQAL |  

600:CKEAGHQGPL | HQCDIYQSTK | AGAKLQQVLQ | AGCSRPWQEV | LKDLVGSDAL |  

650:DASALMEYFQ | PVSQWLQEQN | QRNGEVLGWP | EYQWRPPLPD | NYPEGIDLET |  

700:DEAKANRFVE | EYDRTAKVLW | NEYAEANWHY | NTNITIEGSK | ILLQKNKEVS |  

750:NHTLKYGTWA | KTFDVSNFQN | STIKRIIKKV | QNVDRAVLPP | NELEEYNQIL |  

800:LDMETTYSVA | NVCYTNGTCL | SLEPDLTNIM | ATSRKYEELL | WVWKSWRDKV |  

850:GRAILPFFPK | YVDFSNKIAK | LNGYSDAGDS | WRSSYESDDL | EQDLEKLYQE |  

900:LQPLYLNLHA | YVRRSLHRHY | GSEYINLDGP | IPAHLLGNMW | AQTWSNIYDL |  

950:VAPFPSAPSI | DATEAMIKQG | WTPRRIFKEA | DNFFTSLGLL | PVPPEFWNKS |  

1000:MLEKPTDGRE | VVCHASAWDF | YNGKDFRIKQ | CTSVNMEELV | IAHHEMGHIQ |  

1050:YFMQYKDLPV | TFREGANPGF | HEAIGDVLAL | SVSTPKHLHS | LNLLSSEGSG |  

1100:YEHDINFLMK | MALDKIAFIP | FSYLIDQWRW | RVFDGSITKE | NYNQEWWSLR |  

1150:LKYQGLCPPV | PRSQGDFDPG | SKFHVPANVP | YIRYFISFII | QFQFHEALCR |  

1200:AAGHTGPLYK | CDIYQSKEAG | KLLADAMKLG | YSKQWPEAMK | IITGQPNMSA |  

1250:SAIMNYFKPL | TEWLVTENRR | HGETLGWPEY | TWTPNTARAE | GSLPESSRVN |  

1300:FLGMYLEPQQ | ARVGQWVLLF | LGVALLVATV | GLAHRLYNIH | NHHSLRRPHR |  

1313:GPQFGSEVEL | RHS

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